The International Center of the DLSU-College of St. Benilde is located on the corner of Arellano Ave. and Estrada St. in Malate, Manila. It is a part of the De La Salle University-College of Saint Benilde campus and houses the School of Hotel, Restaurant, and Institution Management (SHRIM), Career Development Program (CDP), Center for English Language Learning (CELL), Social Development Research Center (SDRC), Caucus for Power Reduction (CPR) and the DLSU-Angelo King Institute for Economic and Business Studies.

The International Center is situated between the commercial and business districts of Manila City. It is 15 minutes away from the entry ramp of the Skyway, which offers the quickest route to the business parks and commercial centers in the south. Easily accessible via Roxas Boulevard or South Superhighway, it is only a 30-minute drive from the Ninoy Aquino International Airport.